I have no frame of reference for that at all, but I think I get the idea anyway.

[Owen himself can't remember feeling uncomfortable in his own skin. It probably happened around puberty, since that's the time for it, but ever since then he either hasn't thought about it or has been pretty satisfied with the results.]

So you really are a woman? [If Loki can ask him about his sexuality, then Owen's gonna be point-blank about this, too.] Not just looking like one, but top-to-bottom?